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High‑pressure PEEK tubing is used in chromatography systems requiring bioinert, metal‑free fluid paths with reliable pressure performance and chemical compatibility. This category includes laboratory‑grade PEEK tubing designed for use in HPLC, UHPLC, LC‑MS, capillary LC, and other sensitive analytical workflows.

PEEK tubing is commonly selected as an alternative to stainless steel when adsorption, metal interaction, or flexibility are a concern.


Material & Manufacturing Characteristics

All PEEK tubing in this category is manufactured from virgin PEEK resin, providing:

  • Excellent chemical resistance

  • Low analyte adsorption

  • High dimensional stability

  • Mechanical strength suitable for high‑pressure chromatography

No additives are introduced into the base PEEK polymer. Color is applied either through controlled pigmentation (solid‑color tubing) or external co‑extrusion (striped tubing), ensuring that performance of the internal fluid path is preserved.

PEEK’s modulus and mechanical properties make it well suited for bioinert applications where stainless steel is undesirable.


PEEK Tubing Types & Selection Guidance

Solid‑Color PEEK Tubing

Solid‑color PEEK tubing is commonly used for routine HPLC applications where flexibility, solvent compatibility, and cost efficiency are important.

Key characteristics:

  • Chemically resistant and flexible

  • Suitable for everyday HPLC use

  • Tolerance: ± 0.05 mm for both ID and OD

  • Most economical PEEK tubing option


Striped Indicator PEEK Tubing

Striped PEEK tubing consists of natural PEEK with an external color stripe applied by co‑extrusion. The color stripe is present only on the outside of the tubing.

Advantages:

  • Maintains a pure PEEK internal surface

  • Provides visual indication of solvent compatibility issues

  • Helps identify tubing ID at a glance

If aggressive solvents interact with the tubing wall, color degradation can indicate that tubing replacement is recommended. For this reason, striped or natural PEEK tubing is generally preferred over pigmented tubing when solvent compatibility is uncertain.

  • Tolerance: ± 0.05 mm for both ID and OD


Ultra‑T™ Precision PEEK Tubing

Ultra‑T™ PEEK tubing is manufactured with significantly tighter dimensional tolerances and is recommended when flow‑volume precision is critical.

Applications include:

  • LC‑MS

  • Capillary LC

  • Micro‑flow and low‑dead‑volume systems

Key characteristics:

  • Tolerance: ± 0.025 mm for both ID and OD

  • Minimizes volumetric variation and flow irregularities

  • Typically, not required for routine analytical HPLC

Ultra‑T™ tubing is selected when even small flow deviations can impact results.


Pressure & Performance Considerations

PEEK tubing supports high‑pressure operation appropriate to its internal diameter and system configuration. Selecting the proper tubing ID and length is essential to:

  • Maintain pressure stability

  • Minimize system dead volume

  • Preserve chromatographic efficiency

Short, well‑routed tubing lengths help improve system performance and reproducibility.


FlexiTubes™ – Coiled PEEK Tubing Option

For applications requiring extended tubing lengths without clutter, FlexiTubes™ coiled PEEK tubing provides a space‑saving solution while maintaining performance. The coiled geometry can also contribute to pulse dampening in certain flow conditions.

👉 View FlexiTubes™ coiled PEEK tubing options


Applications & Use Cases

High‑pressure PEEK tubing is commonly used for:

  • HPLC and UHPLC solvent delivery

  • LC‑MS fluid paths

  • Bioinert analytical workflows

  • Method development and system optimization

  • Capillary and micro‑flow chromatography


Fittings & Compatibility Guidance

PEEK tubing performance depends on proper fitting selection.

👉 View HPLC connection fittings

For mobile‑phase connections immersed directly in solvents, it is recommended to use PEEK or ETFE fittings and ferrules for chemical compatibility and long‑term reliability.

👉 Learn more about selecting fittings for solvent‑immersed connections


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